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We carry popular Mitragyna Speciosa such as Red Vein Maeng Da, Green Vein Maeng Da, Red Vein Bali, Malay, Sumatra.
Our Presentation: Kratom Powder, Kratom Capsules, Kratom Extracts
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Respiratory effects of oral mitragynine and oxycodone in a rodent model.
Compare the respiratory effects of oral mitragynine to oral oxycodone in rats for evaluating effects of opioids
Consistent with mitragynine’s pharmacology that includes partial µ-opioid receptor agonism with little recruitment of the respiratory depressant activating β-arrestin pathway, mitragynine produced no evidence of respiratory depression at doses many times higher than known to be taken by humans.
Kratom - Biological Effects and Chemical Composition
Chemical composition and biological effects of kratom. In vitro studies with implications for efficacy and substance interactions
The safety and efficacy of kratom (Mitragyna speciosa) for treatment of pain is highly controversial. Kratom produces more than 40 structurally related alkaloids, but most studies have focused on just two of these, mitragynine and 7-hydroxymitragynine.
What is Kratom? - National Institute of Health overview of Kratom
“Kratom” commonly refers to an herbal substance that can produce opioid- and stimulant-like effects. Kratom and kratom-based products are currently legal and accessible in many areas, though U.S. and international agencies continue to review emerging evidence to inform kratom policy.
While there are no uses for kratom approved by the U.S. Food and Drug Administration, people report using kratom to manage drug withdrawal symptoms and cravings (especially related to opioid use), pain, fatigue and mental health problems. NIDA supports and conducts research to evaluate potential medicinal uses for kratom and related chemical compounds.
Kratom-Pharmacology, Clinical Implications and Deep Review
The prevalence of kratom use appears to be increasing in Europe and North America, raising concerns for its possible development into a significant public health threat.
The body of scientific literature concerning kratom is expanding, but has not yet sufficiently characterized the nature and extent of the potential risks posed by kratom.
There is an increasing need for healthcare providers to be familiar with kratom and the management of patients who abuse it.
Remarkable Herbs Kratom Review, learn about their products and quality control standards that have made them one of the best kratom brands. Built up a solid reputation over the years. It has AKA certification and its selection of herbs can be found in shops nationwide
Does kratom cause liver damage? Kratom Liver toxicity
There are over a thousand substances capable of causing liver injury. Similarly, Herb-Induced Liver Injury (HILI) is also recognized as liver damage from herbal dietary supplements or medicines.
You may have heard of the negative kratom liver effects. but does kratom cause liver damage? Find out here.