ZUMVU

#Respiratorydepression

Kratom Lords
Posted on 02 November 2022 at 01:10AM
Respiratory effects of oral mitragynine and oxycodone in a rodent model.

Compare the respiratory effects of oral mitragynine to oral oxycodone in rats for evaluating effects of opioids

Consistent with mitragynine’s pharmacology that includes partial µ-opioid receptor agonism with little recruitment of the respiratory depressant activating β-arrestin pathway, mitragynine produced no evidence of respiratory depression at doses many times higher than known to be taken by humans.

#Kratom #Mitragynine #Oxycodone #Safety #Respiratorydepression #Rat #Animalmodel #Pharmacokinetics #Pharmacodynamics #Opioidepidemic #research #study

https://kratomlords.com/kratom-research/respiratory-effects-mitragynine-oxycodone/
Respiratory effects of oral mitragynine and oxycodone kratomlords.com Compare the respiratory effects of oral mitragynine to oral oxycodone in rats for evaluating the respiratory effects of opioids