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We carry popular Mitragyna Speciosa such as Red Vein Maeng Da, Green Vein Maeng Da, Red Vein Bali, Malay, Sumatra.
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Therapeutic potential and liability of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine.
Kratom, derived from the plant Mitragyna speciosa, is receiving increased attention as an alternative to traditional opiates and as a replacement therapy for opiate dependence.
The increasing use of kratom has emerged as a public health concern in the US.
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Any beginner who is getting into the world of kratom wanting to get their hands on the best kratom strains have gone through the same route many of us have: They hear about kratom from friends or family and slowly head way to to their local smoke shops where they are greeted by a variety of kratom brands. Some even buy kratom online. Through this they understand that the quality of kratom and kratom’s effects vary from strain to strain. Even a slight variation in kratom’s alkaloid profile can cause a big difference in the user’s experience. So yes, it does matter where you buy kratom from.
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Respiratory effects of oral mitragynine and oxycodone in a rodent model.
Compare the respiratory effects of oral mitragynine to oral oxycodone in rats for evaluating effects of opioids
Consistent with mitragynine’s pharmacology that includes partial µ-opioid receptor agonism with little recruitment of the respiratory depressant activating β-arrestin pathway, mitragynine produced no evidence of respiratory depression at doses many times higher than known to be taken by humans.
atai Life Sciences - Phase 1 trial of kratom-derived pharmaceutical
atai and Kures are poised to address two key factors underlying the opioid epidemic developing a potentially safer and more widely available alternative for both pain management and opioid maintenance therapy.
One of the leading therapeutic indicators of kratom is its analgesic effect. One study of Kratom users in Malaysia showed that 90% were using kratom as a substitute for opioids, with 84% reporting that kratom eased their opioid withdrawal symptoms.
