Kratom - Biological Effects and Chemical Composition
Chemical composition and biological effects of kratom. In vitro studies with implications for efficacy and substance interactions
The safety and efficacy of kratom (Mitragyna speciosa) for treatment of pain is highly controversial. Kratom produces more than 40 structurally related alkaloids, but most studies have focused on just two of these, mitragynine and 7-hydroxymitragynine.
The Antidepressant-Like and Analgesic Effects of Kratom
Kratom employed as a traditional medicine to improve mood and relieve pain, has shown increased use in Europe and North America. Here, the dose-dependent effects of a purified alkaloid kratom extract on neuronal oscillatory systems function, analgesia, and antidepressant-like behaviour were evaluated and kratom-induced changes in ΔFosB expression determined.
Kratom-Pharmacology, Clinical Implications and Deep Review
The prevalence of kratom use appears to be increasing in Europe and North America, raising concerns for its possible development into a significant public health threat.
The body of scientific literature concerning kratom is expanding, but has not yet sufficiently characterized the nature and extent of the potential risks posed by kratom.
There is an increasing need for healthcare providers to be familiar with kratom and the management of patients who abuse it.
Some people have experienced different effects, including weight loss. However, there are also users who report that kratom may be making them gain weight. But, is this possible? Does kratom cause weight gain? We’ll explore this subject in this article.