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We carry popular Mitragyna Speciosa such as Red Vein Maeng Da, Green Vein Maeng Da, Red Vein Bali, Malay, Sumatra.
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Respiratory effects of oral mitragynine and oxycodone in a rodent model.
Compare the respiratory effects of oral mitragynine to oral oxycodone in rats for evaluating effects of opioids
Consistent with mitragynine’s pharmacology that includes partial µ-opioid receptor agonism with little recruitment of the respiratory depressant activating β-arrestin pathway, mitragynine produced no evidence of respiratory depression at doses many times higher than known to be taken by humans.
Comprehensive real-time Kratom coverage, aggregated from sources all over the internet by Kratom Lords.
Find helpful hints, tips, and news about kratom. Ask questions, share answers, discuss kratom strains and kratom effects. Discover kratom legality, cultivation, and also methods for quitting kratom.
Therapeutic potential and liability of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine.
Kratom, derived from the plant Mitragyna speciosa, is receiving increased attention as an alternative to traditional opiates and as a replacement therapy for opiate dependence.
The increasing use of kratom has emerged as a public health concern in the US.
What is Kratom? - National Institute of Health overview of Kratom
“Kratom” commonly refers to an herbal substance that can produce opioid- and stimulant-like effects. Kratom and kratom-based products are currently legal and accessible in many areas, though U.S. and international agencies continue to review emerging evidence to inform kratom policy.
While there are no uses for kratom approved by the U.S. Food and Drug Administration, people report using kratom to manage drug withdrawal symptoms and cravings (especially related to opioid use), pain, fatigue and mental health problems. NIDA supports and conducts research to evaluate potential medicinal uses for kratom and related chemical compounds.
Some people have experienced different effects, including weight loss. However, there are also users who report that kratom may be making them gain weight. But, is this possible? Does kratom cause weight gain? We’ll explore this subject in this article.