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Safety is especially important when using extended-release opioid medications. OxyContin OC 40 mg should only be used by the person for whom it was prescribed. Combining oxycodone with alcohol, benzodiazepines, or other sedatives can increase the risk of respiratory depression and overdose. Tablets must be swallowed whole according to prescribing instructions. Patients should never adjust their treatment independently. Keep medication securely stored away from children and other individuals. Medical supervision helps identify potential complications and supports safer treatment decisions.