QuickBooks not responding when opening company file can be due to corrupted data, a damaged installation, or system conflicts. Ensure QuickBooks and your operating system are up-to-date. Run the QuickBooks File Doctor to repair the company file. Temporarily disable antivirus software, and try opening the file in Safe Mode. If the issue persists, consider seeking professional technical support to diagnose and fix the problem. For immediate assistance, please contact our QuickBooks Experts Team at +1–855–409–2300.