Tramadol is a pharmaceutical pain reliever that is helpful to treat moderate to severe pain. #Tramadol and its active metabolite bind to mu-opioid receptors in the central nervous system (brain and spinal cord), activating inhibitory neurons and decreasing pain signals. It also appears to weakly impede serotonin and norepinephrine reuptake, raising their levels in the neuronal synapse. #health, #painkiller